Malaysia

GENGIGEL is a medical device containing high molecular weight ( HMW ) hyaluronic acid ( in the form of sodium hyaluronate ), obtained by a biotechnological manufacturing process, which guarantees a high level of purity. Its formulation is specifically created in order to resemble that of the hyaluronic acid found in normal gingival tissue. 

Hyaluronic acid is a naturally occurring physiological constituent of connective tissue ( especially in the gingival mucosa ), where it performs antioedematous and tissue repair functions. The physico-chemical and macro aggregating properties of hyaluronic acid helps to explain it's antiinflammatory properties. HMW hyaluronic acid is found in connective tissue throughout the body in a selective and specific manner. It is particularly concentrated in the outermost layers of healthy gingival tissue where it contributes to both the barrier function and tensile strength of the periodontal ligament. 

The presence of HMW hyaluronic acid is essential for the maintenance of the healthy gingival tissue. GENGIGEL is therefore an innovative product providing long acting biotechnologically manufactured hyaluronic acid of High Molecular Weight. Application of hyaluronic acid provides periodontal tissue/fluid balance with accelerated healing and repair functions by preventing the deficiency of natural gingival HMW hyaluronic aid and enhancing its effects. 

Hyaluronic acid does not develop and local or systemic pharmacological effect upon the mucosa. Hyaluronic acid is extensively depolymerised and reduced to its basic sub-unit constituents by plaque bacterial enzyme action.