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The consumption of 400 mg papaya seed juice is able to lower total cholesterol levels to 128.28 mg / dl from original 257.57 mg / dl. Nuraeni Cheek Research and colleagues from the Faculty of Medical and Health Science, Muhammadiyah Yogyakarta University.*** The giving of dragon fruit supplement is 1.17% capable of lowering the total cholesterol by up to 59.06%. It was followed by deforming the low density value of lipoprotein (LDL) aka bad cholesterol. The prominent LDL level reaches 6080%. While high density lipoprotein (HDL) aka cholesterol is good increased average to 25%. Praclinical research by R Mohd Adzyme Khalili and A Norhayati from Management and Science University, M Y Rockey, R As-friendly and M Siti Muskinah of University of the Malaysia Son, as well as the Manaf Abdul of the Faith Darul University.*** Researches of Anugrah Riansari and Suhardjono from the Faculty of Diponegoro University Medicine shows 0.72 g consumption per kg body weight Syzygium polyanthum greeting leaf extract is able to lower total cholesterol levels of up to 43.48 mg/dL.*** Novi Cynthia Goddess Prism of the Nutritional Science Program Diponegoro University Semarang proves consumption of 0.45 g green bean extract can lower bad cholesterol levels (LDL) to 21.06%